DBF4 Antikörper (AA 295-665)
Kurzübersicht für DBF4 Antikörper (AA 295-665) (ABIN7873463)
Target
Alle DBF4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 295-665
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Verwendungszweck
- DBF4 Antibody
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Aufreinigung
- Affinity purified
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Immunogen
- Recombinant human protein (amino acids Y295-S665) was used as the immunogen for the DBF4 antibody.
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Isotyp
- IgG
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Applikationshinweise
- Optimal dilution of the DBF4 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- After reconstitution, the DBF4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- DBF4 (DBF4 Homolog (DBF4))
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Andere Bezeichnung
- DBF4
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Hintergrund
- Using both gain- and loss-of-function experiments, it was found that Xenopus Dbf4 inhibited canonical Wnt signaling. Depletion of endogenous Dbf4 did not disturb gastrulation movements or early organizer genes, but resulted in embryos with morphologically defective heart and eyes and suppressed cardiac markers. The function of Dbf4 in heart development appeared to be independent of its role in the cell cycle. Dbf4 interacted physically and functionally with Frodo, a context-dependent regulator of Wnt signaling.
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UniProt
- Q9UBU7
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Pathways
- Mitotic G1-G1/S Phases, DNA Replication
Target
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