JHDM1D Antikörper (AA 290-316)

Produktnummer ABIN7873439

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch JHDM1D in WB, FACS und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für JHDM1D Antikörper (AA 290-316) (ABIN7873439)

Target: JHDM1D (Jumonji C Domain-Containing Histone Demethylase 1 Homolog D (JHDM1D))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JHDM1D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-JHDM1D Antikörper

Bindungsspezifität: AA 290-316

Verwendungszweck: JHDM1D Antibody / KDM7A

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 290-316 from the human protein was used as the immunogen for the JHDM1D antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the JHDM1D antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the JHDM1D antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu JHDM1D

Target: JHDM1D (Jumonji C Domain-Containing Histone Demethylase 1 Homolog D (JHDM1D))

Andere Bezeichnung: JHDM1D

Hintergrund: JHDM1D histone demethylase that specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3, thereby playing a central role in histone code. This specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. This demethylates H3K9me2 in absence of H3K4me3.

UniProt: Q6ZMT4