Rekombinanter Occludin Antikörper (AA 282-415)
Kurzübersicht für Rekombinanter Occludin Antikörper (AA 282-415) (ABIN7873302)
Target
Alle Occludin (OCLN) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- AA 282-415
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Verwendungszweck
- OCLN Antibody / Occludin (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- A recombinant human protein fragment (within amino acids 282-415) was used as the immunogen for the OCLN antibody.
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Isotyp
- IgG1, kappa
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anti-Occludin (OCLN) (AA 431-522) antibody
OCLN Reaktivität: Human, Maus, Schwein WB, ELISA, FACS, IHC (p), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Occludin (OCLN) (C-Term) antibodyOCLN Reaktivität: Human, Maus, Ratte, Hund, Affe WB, IHC (p), IHC (fro) Wirt: Ziege Polyclonal unconjugated
anti-Occludin (OCLN) (AA 423-522) antibodyOCLN Reaktivität: Human WB, ELISA, IP, IF Wirt: Maus Monoclonal 1G7 unconjugated
anti-Occludin (OCLN) (AA 1-522) antibodyOCLN Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated
anti-Occludin (OCLN) (AA 1-522) antibodyOCLN Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Occludin (OCLN) (AA 282-415) antibodyOCLN Reaktivität: Human WB, IHC Wirt: Maus Monoclonal OCLN-2181 unconjugated
anti-Occludin (OCLN) (AA 54-270) antibodyOCLN Reaktivität: Human WB, IHC, ELISA, FACS, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Occludin (OCLN) (C-Term) antibodyOCLN Reaktivität: Human, Maus, Ratte, Hund WB, IHC, ELISA, IF, IHC (p) Wirt: Maus Monoclonal OC-3F10 unconjugated
anti-Occludin (OCLN) (AA 285-430) antibodyOCLN Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Occludin (OCLN) (AA 350-450) antibodyOCLN Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal dilution of the OCLN antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the OCLN antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Occludin (OCLN)
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Andere Bezeichnung
- OCLN
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Hintergrund
- Occludin is a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures that can contain two extracellular loops. The protein exists in a variety of phosphorylated forms. Phosphorylation is involved in regulating both the localization and the function of Occludin. Expression of Occludin is upregulated by polyunsaturated fatty acids, increasing trans-endothelial cell resistance and reducing cellular permeability to large molecules. The level of Occludin varies greatly depending on tissue, in brain tissue, Occludin is highly expressed at cell-cell contact sites. Non-neural tissues show lower expression and discontinuous distribution. Up-regulation of epithelial Occludin may play a role in enhancing paracellular permeability and be related to the damage to the tight junction.
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UniProt
- Q16625
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Pathways
- Cell-Cell Junction Organization, Hepatitis C
Target
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