RCC2 Antikörper (AA 266-495)

Produktnummer ABIN7873057

Der Kaninchen Polyklonal anti-RCC2 Antikörper (ABIN7873057) detektiert spezifisch RCC2 in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Zebrafisch (Danio rerio).

Kurzübersicht für RCC2 Antikörper (AA 266-495) (ABIN7873057)

Target: RCC2 (Regulator of Chromosome Condensation 2 (RCC2))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RCC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RCC2 Antikörper

Bindungsspezifität: AA 266-495

Verwendungszweck: Zebrafish Rcc2 Antibody / Protein RCC2 homolog

Aufreinigung: Antigen affinity chromatography

Immunogen: E. coli-derived zebrafish Rcc2 recombinant protein (amino acids K266-L495) was used as the immunogen for the Zebrafish Rcc2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish Rcc2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish Rcc2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu RCC2

Target: RCC2 (Regulator of Chromosome Condensation 2 (RCC2))

Andere Bezeichnung: Rcc2

Hintergrund: Zebrafish Rcc2, known as regulator of chromosome condensation 2, is a multifunctional protein that plays a role in cell cycle progression, cytoskeletal dynamics, and cellular signaling. It is particularly involved in mitotic events, where it regulates processes related to chromosome condensation and segregation. Rcc2 is also known to interact with small GTP binding proteins such as Rac1, thereby influencing cell migration, adhesion, and actin cytoskeleton organization.

Zebrafish Rcc2 is an ortholog of the human RCC2 protein and shares significant sequence and functional similarity. In both species, Rcc2 functions as part of the chromosomal passenger complex and contributes to the accurate distribution of chromosomes during mitosis. Disruption of Rcc2 function can impair cell division and affect developmental processes, making it a key protein for studies of cell proliferation and morphogenesis.

Research on zebrafish Rcc2 is valuable for understanding its conserved roles in cell cycle regulation and cytoskeletal rearrangements. Zebrafish models allow for the exploration of Rcc2 function during embryogenesis, where rapid and precise cell division is essential for normal development.

Antibodies targeting zebrafish Rcc2 protein are important tools for studying mitosis, cytoskeletal organization, and related signaling pathways. The orthology between zebrafish Rcc2 and human RCC2 supports the use of zebrafish as a model to investigate fundamental mechanisms of cell division and to study pathways that may be altered in diseases such as cancer.

UniProt: Q6NYE2