NAD-ME Antikörper (AA 26-584)

Produktnummer ABIN7873011

Der Kaninchen Polyklonal anti-NAD-ME Antikörper wird verwendet zum Nachweis von NAD-ME in Proben von Human, Maus, Ratte und Affe. Er wurde validiert für WB, ELISA, IF und IHC (p).

Kurzübersicht für NAD-ME Antikörper (AA 26-584) (ABIN7873011)

Target: NAD-ME (NAD Dependent Malate Dehydrogenase (NAD-ME))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAD-ME Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-NAD-ME Antikörper

Bindungsspezifität: AA 26-584

Verwendungszweck: ME2 Antibody / NAD-ME

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids K26-E584) was used as the immunogen for the ME2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ME2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the ME2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu NAD-ME

Target: NAD-ME (NAD Dependent Malate Dehydrogenase (NAD-ME))

Andere Bezeichnung: ME2

Hintergrund: NAD-dependent malic enzyme, mitochondrial is a protein that in humans is encoded by the ME2 gene. It is mapped to 18q21.2. This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.

UniProt: P23368

Pathways: Production of Molecular Mediator of Immune Response