PYROXD1 Antikörper (AA 26-453)

Produktnummer ABIN7873006

Der Kaninchen Polyklonal anti-PYROXD1 Antikörper (ABIN7873006) detektiert spezifisch PYROXD1 in WB, ELISA, FACS und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für PYROXD1 Antikörper (AA 26-453) (ABIN7873006)

Target: PYROXD1 (Pyridine Nucleotide-Disulphide Oxidoreductase Domain 1 (PYROXD1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PYROXD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails anti-PYROXD1 Antikörper

Bindungsspezifität: AA 26-453

Verwendungszweck: PYROXD1 Antibody / Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids A26-N453) was used as the immunogen for the PYROXD1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PYROXD1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the PYROXD1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu PYROXD1

Target: PYROXD1 (Pyridine Nucleotide-Disulphide Oxidoreductase Domain 1 (PYROXD1))

Andere Bezeichnung: PYROXD1

Hintergrund: Pyridine nucleotide-disulphide oxidoreductase domain 1 is a protein that in humans is encoded by the PYROXD1 gene. It is mapped to 12p12.1. This gene encodes a nuclear-cytoplasmic pyridine nucleotide-disulphide reductase (PNDR). PNDRs are flavoproteins that catalyze the pyridine nucleotide-dependent reduction of thiol residues in other proteins. The encoded protein belongs to the class I pyridine nucleotide-disulphide oxidoreductase family but lacks the C-terminal dimerization domain found in other family members and instead has a C-terminal nitrile reductase domain. It localizes to the nucleus and to striated sarcomeric compartments. Naturally occurring mutations in this gene cause early-onset myopathy with internalized nuclei and myofibrillar disorganization. A pseudogene of this gene has been defined on chromosome 11.

UniProt: Q8WU10