GATA6 Antikörper (AA 26-296)

Produktnummer ABIN7872994

Der Kaninchen Polyklonal anti-GATA6 Antikörper (ABIN7872994) detektiert spezifisch GATA6 in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Zebrafisch (Danio rerio).

Kurzübersicht für GATA6 Antikörper (AA 26-296) (ABIN7872994)

Target: GATA6 (GATA Binding Protein 6 (GATA6))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GATA6 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GATA6 Antikörper

Bindungsspezifität: AA 26-296

Verwendungszweck: Zebrafish Gata6 Antibody / GATA-binding factor 6

Aufreinigung: Antigen affinity chromatography

Immunogen: E. coli-derived zebrafish Gata6 recombinant protein (amino acids E26-E296) was used as the immunogen for the Zebrafish Gata6 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish Gata6 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish Gata6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu GATA6

Target: GATA6 (GATA Binding Protein 6 (GATA6))

Andere Bezeichnung: Gata6

Hintergrund: GATA-binding protein 6 (Gata6) is a zinc finger transcription factor belonging to the GATA family, which regulates gene expression during embryonic development and cell lineage specification. In zebrafish (Danio rerio), Gata6 plays a key role in the development of the endoderm, heart, and gut, as well as in organ morphogenesis and tissue differentiation.

During early zebrafish embryogenesis, Gata6 is expressed in the endodermal and mesodermal layers, where it works in concert with Gata4 and Gata5 to specify endodermal fate and initiate the morphogenesis of organs such as the liver, pancreas, and intestine. It also contributes to cardiac progenitor specification and the formation of the heart tube, making it essential for proper cardiovascular development.

Due to its high conservation and central role in organogenesis, zebrafish Gata6 is widely used as a model to study developmental gene regulation, cardiogenesis, and congenital diseases affecting the heart and gastrointestinal tract. It is also a valuable marker for analyzing endodermal derivatives and early tissue patterning in vertebrate embryos.

UniProt: Q6NW63