PIEZO2 Antikörper (AA 2575-2604)

Produktnummer ABIN7872967

Der Kaninchen Polyklonal anti-PIEZO2 Antikörper (ABIN7872967) detektiert spezifisch PIEZO2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PIEZO2 Antikörper (AA 2575-2604) (ABIN7872967)

Target: PIEZO2 (FAM38B) (Family with Sequence Similarity 38, Member B (FAM38B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIEZO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PIEZO2 Antikörper

Bindungsspezifität: AA 2575-2604

Verwendungszweck: PIEZO2 Antibody / FAM38B

Aufreinigung: Antigen affinity

Immunogen: A portion of amino acids 2575-2604 from the human protein was used as the immunogen for the PIEZO2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the PIEZO2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the PIEZO2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu PIEZO2

Target: PIEZO2 (FAM38B) (Family with Sequence Similarity 38, Member B (FAM38B))

Andere Bezeichnung: PIEZO2

Hintergrund: PIEZO2 (Piezo-type mechanosensitive ion channel component 2), also called Protein FAM38B, is a transmembrane protein that spans the cell membrane and acts as a sensor for mechanical stimuli. When external forces, such as touch or pressure, are applied to the cell membrane, PIEZO2 responds by opening up and allowing ions to flow into the cell. This influx of ions triggers a signal that is transmitted to the brain, allowing us to perceive and respond to the touch sensation. It also plays a critical role in a variety of other sensory functions, including proprioception (the ability to sense the position of our body in space) and hearing. Recent studies have uncovered even more functions of PIEZO2 beyond sensory perception. It has been found to be involved in regulating lung development, bone formation, and even cell migration.

UniProt: Q9H5I5