IL1RL2 Antikörper (AA 257-286)

Produktnummer ABIN7872954

Der Kaninchen Polyklonal anti-IL1RL2 Antikörper wird verwendet zum Nachweis von IL1RL2 in Proben von Human. Er wurde validiert für WB und FACS.

Kurzübersicht für IL1RL2 Antikörper (AA 257-286) (ABIN7872954)

Target: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL1RL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-IL1RL2 Antikörper

Bindungsspezifität: AA 257-286

Verwendungszweck: IL1RL2 Antibody / Interleukin-1 receptor-like 2

Aufreinigung: Antigen affinity

Immunogen: A portion of amino acids 257-286 from the human protein was used as the immunogen for this IL1RL2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the IL1RL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4oC for up to one month. For long term, aliquot the IL1RL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu IL1RL2

Target: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Andere Bezeichnung: IL1RL2

Hintergrund: IL1RL2, also known as interleukin-1 receptor-like 2, is a protein that belongs to the IL-1 receptor family. It is primarily expressed on the surface of immune cells, where it binds to specific ligands and triggers a cascade of signaling pathways that ultimately lead to the activation of immune responses. Studies have shown that IL1RL2 plays a critical role in the pathogenesis of various inflammatory diseases, such as asthma, rheumatoid arthritis, and inflammatory bowel disease. One of the key functions of IL1RL2 is its ability to regulate the production of pro-inflammatory cytokines, such as IL-6 and IL-8, which are responsible for promoting inflammation in the body. By modulating the activity of these cytokines, IL1RL2 helps to maintain the balance between pro-inflammatory and anti-inflammatory responses, thereby preventing excessive inflammation and tissue damage. Furthermore, IL1RL2 has also been shown to play a role in the activation of T cells and other immune cells, which are essential for mounting an effective immune response against pathogens.

UniProt: Q9HB29