SH3BP2 Antikörper (AA 256-561)

Produktnummer ABIN7872952

Der Kaninchen Polyklonal anti-SH3BP2 Antikörper (ABIN7872952) detektiert spezifisch SH3BP2 in WB, ELISA und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für SH3BP2 Antikörper (AA 256-561) (ABIN7872952)

Target: SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SH3BP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-SH3BP2 Antikörper

Bindungsspezifität: AA 256-561

Verwendungszweck: 3BP2 Antibody / SH3 domain-binding protein 2 / SH3BP2

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R256-R561) was used as the immunogen for the 3BP2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the 3BP2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the 3BP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu SH3BP2

Target: SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))

Andere Bezeichnung: 3BP2

Hintergrund: SH3BP2 (SH3 domain-binding protein 2) is a protein that comes from a gene located on Chromosome 4. The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: P78314

Pathways: T-Zell Rezeptor Signalweg