Rhotekin Antikörper (AA 255-554)

Produktnummer ABIN7872939

Der Kaninchen Polyklonal anti-Rhotekin Antikörper wird verwendet zum Nachweis von Rhotekin in Proben von Human. Er wurde validiert für WB, ELISA und FACS.

Kurzübersicht für Rhotekin Antikörper (AA 255-554) (ABIN7872939)

Target: Rhotekin (RTKN)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Rhotekin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-Rhotekin Antikörper

Bindungsspezifität: AA 255-554

Verwendungszweck: Rhotekin Antibody / RTKN

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R255-Q554) was used as the immunogen for the Rhotekin antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Rhotekin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Rhotekin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Rhotekin

Target: Rhotekin (RTKN)

Andere Bezeichnung: Rhotekin

Hintergrund: Rhotekin is a protein that in humans is encoded by the RTKN gene. This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: Q9BST9