Rekombinanter LI Cadherin Antikörper (AA 242-418)

Produktnummer ABIN7872767

Dieser Maus Monoklonal Antikörper detektiert spezifisch LI Cadherin in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter LI Cadherin Antikörper (AA 242-418) (ABIN7872767)

Target: LI Cadherin

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LI Cadherin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RCDH17-8514

Produktdetails anti-LI Cadherin Antikörper

Bindungsspezifität: AA 242-418

Verwendungszweck: LI Cadherin Antibody / Cadherin 17

Aufreinigung: Protein A affinity

Immunogen: A recombinant partial protein sequence (within amino acids 242-418) from the human protein was used as the immunogen for the LI Cadherin antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the LI Cadherin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the LI Cadherin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu LI Cadherin

Target: LI Cadherin

Hintergrund: It recognizes a protein of 120 kDa, which is identified as Cadherin 17 (also known as LI Cadherin). The cadherins are a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.

UniProt: Q12864