PAX2A Antikörper (AA 240-282)

Produktnummer ABIN7872729

Der Kaninchen Polyklonal anti-PAX2A Antikörper wird verwendet zum Nachweis von PAX2A in Proben von Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für PAX2A Antikörper (AA 240-282) (ABIN7872729)

Target: PAX2A (Paired Box Gene 2a (PAX2A))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAX2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PAX2A Antikörper

Bindungsspezifität: AA 240-282

Verwendungszweck: Zebrafish Pax2 Antibody / Pax2a / Pax2b

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Pax2 recombinant protein (amino acids E240-Q282) was used as the immunogen for the Zebrafish Pax2 antibody. This antibody will detect the a and b isoforms.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish Pax2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish Pax2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu PAX2A

Target: PAX2A (Paired Box Gene 2a (PAX2A))

Andere Bezeichnung: Pax2

Hintergrund: Paired box gene 2, also known as PAX2, is a protein which in humans is encoded by the PAX2 gene. This gene is mapped to 10q24. PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.

UniProt: Q90268

Pathways: Carbohydrate Homeostasis, Stem Cell Maintenance, Tube Formation