DCT Antikörper (AA 24-519)

Produktnummer ABIN7872702

Der Kaninchen Polyklonal anti-DCT Antikörper wird verwendet zum Nachweis von DCT in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA und FACS.

Kurzübersicht für DCT Antikörper (AA 24-519) (ABIN7872702)

Target: DCT (Dopachrome Tautomerase (DCT))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-DCT Antikörper

Bindungsspezifität: AA 24-519

Verwendungszweck: DCT Antibody / L-dopachrome tautomerase / TYRP2 / TRP2

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids Q24-A519) was used as the immunogen for the DCT antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the DCT antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the DCT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu DCT

Target: DCT (Dopachrome Tautomerase (DCT))

Andere Bezeichnung: DCT

Hintergrund: Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), also known as DCT, is a human gene. The TYR-related proteins, TRP1 and TRP2, are also specifically expressed in melanocytes, and they likewise contribute to the synthesis of melanin within the melanosomes. The TRPs, including TYR, all share a similar transmembrane region, contain two metal-binding regions and a cysteinerich epidermal growth factor motif, and are localized in the melanosomal membrane. These proteins, however, have distinct catalytic activity, and they individually contribute to the biosynthesis of melanin biopolymers. The TRPs are believed to exist as a multi-enzyme complex, as these proteins form aggregates together, and the expression of TRP1 also helps stabilize TYR in melanocytes.

UniProt: P40126