FcRn Antikörper (AA 24-215)

Produktnummer ABIN7872674

Dieser Maus Monoklonal Antikörper detektiert spezifisch FcRn in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für FcRn Antikörper (AA 24-215) (ABIN7872674)

Target: FcRn (neonatal Fc Receptor (FcRn))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FcRn Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: FCGRT-2932

Produktdetails anti-FcRn Antikörper

Bindungsspezifität: AA 24-215

Verwendungszweck: FCGRT Antibody / FcRn (azide and preservative free)

Aufreinigung: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 24-215) was used as the immunogen for the FCGRT antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the FCGRT antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the FCGRT antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu FcRn

Target: FcRn (neonatal Fc Receptor (FcRn))

Andere Bezeichnung: FCGRT

Hintergrund: This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. FCGRT is present in the intestinal epithelium of neonates and mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn to acquire passive immunity. FCGRT is comprised of a heavy chain and -2-Microglobulin. FCGRT localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal degradation.

UniProt: P55899

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process