Desmoglein 2 Antikörper (AA 24-1020)

Produktnummer ABIN7872661

Der Kaninchen Polyklonal anti-Desmoglein 2 Antikörper (ABIN7872661) detektiert spezifisch Desmoglein 2 in WB, ELISA, IF, FACS und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Desmoglein 2 Antikörper (AA 24-1020) (ABIN7872661)

Target: Desmoglein 2 (DSG2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Desmoglein 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Desmoglein 2 Antikörper

Bindungsspezifität: AA 24-1020

Verwendungszweck: Desmoglein 2 Antibody / DSG2

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids L24-E1020) was used as the immunogen for the Desmoglein 2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Desmoglein 2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Desmoglein 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Desmoglein 2

Target: Desmoglein 2 (DSG2)

Andere Bezeichnung: Desmoglein 2

Hintergrund: Desmoglein-2 is a protein that in humans is encoded by the DSG2 gene. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in DSG2 display a high degree of penetrance. Disease expression was of variable severity with LV involvement a prominent feature. The low prevalence of classical ECG changes highlights the need to expand current diagnostic criteria to take account of LV disease, childhood disease expression, and incomplete penetrance.

UniProt: Q14126

Pathways: Cell-Cell Junction Organization