Desmoglein 2 Antikörper (AA 24-1020)

Produktnummer ABIN7872660

Der Maus Monoklonal anti-Desmoglein 2 Antikörper wird verwendet zum Nachweis von Desmoglein 2 in Proben von Human. Er wurde validiert für WB und IHC (p).

Kurzübersicht für Desmoglein 2 Antikörper (AA 24-1020) (ABIN7872660)

Target: Desmoglein 2 (DSG2)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Desmoglein 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 2B4D1

Produktdetails anti-Desmoglein 2 Antikörper

Bindungsspezifität: AA 24-1020

Verwendungszweck: DSG2 Antibody / Desmoglein 2

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids L24-E1020) was used as the immunogen for the DSG2 antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the DSG2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the DSG2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Desmoglein 2

Target: Desmoglein 2 (DSG2)

Andere Bezeichnung: DSG2

Hintergrund: Desmoglein-2 is a protein that in humans is encoded by the DSG2 gene. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in DSG2 display a high degree of penetrance. Disease expression was of variable severity with LV involvement a prominent feature. The low prevalence of classical ECG changes highlights the need to expand current diagnostic criteria to take account of LV disease, childhood disease expression, and incomplete penetrance.

UniProt: Q14126

Pathways: Cell-Cell Junction Organization