MMS19 Antikörper (AA 239-998)

Produktnummer ABIN7872659

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MMS19 in WB, ELISA, FACS, IF und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für MMS19 Antikörper (AA 239-998) (ABIN7872659)

Target: MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMS19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MMS19 Antikörper

Bindungsspezifität: AA 239-998

Verwendungszweck: MMS19 Antibody

Aufreinigung: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (E239-R998) was used as the immunogen for the MMS19 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the MMS19 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the MMS19 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu MMS19

Target: MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))

Andere Bezeichnung: MMS19

Hintergrund: MMS19 nucleotide excision repair protein homolog is a protein that in humans is encoded by the MMS19 gene. MMS19 (MMS19 nucleotide excision repair homolog), also known as MET18, is a 1,030 amino acid nuclear protein containing seven HEAT repeats that belongs to the MET18/MMS19 family. Via its interactions with TFIIH p80 and TFIIH p89 helicases, MMS19 plays a role in nucleotide excision repair (NER) and RNA polymerase II (Pol II) transcription. MMS19 may also function as a transcriptional coactivator of estrogen receptor. While ubiquitously expressed, highest levels of MMS19 have been found in testis. At least five distinct MMS19 protein isoforms exist, which are produced by alternative splicing events.

UniProt: Q96T76

Pathways: Nuclear Hormone Receptor Binding