MPND Antikörper (AA 239-471)

Produktnummer ABIN7872649

Der Kaninchen Polyklonal anti-MPND Antikörper (ABIN7872649) detektiert spezifisch MPND in WB, ELISA und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für MPND Antikörper (AA 239-471) (ABIN7872649)

Target: MPND (MPN Domain Containing (MPND))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MPND Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-MPND Antikörper

Bindungsspezifität: AA 239-471

Verwendungszweck: MPND Antibody / MPN domain-containing protein

Aufreinigung: Immunogen affinity purified

Immunogen: E.coli-derived human MPND recombinant protein (Position: R239-S471) was used as the immunogen for the MPND antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the MPND antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the MPND antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu MPND

Target: MPND (MPN Domain Containing (MPND))

Andere Bezeichnung: MPND

Hintergrund: MPND antibody detects MPN domain-containing protein, encoded by the MPND gene. MPN domain-containing protein is a nuclear protein with poorly defined functions but is thought to participate in chromatin regulation, protein interactions, and ubiquitin-like modification processes. MPND antibody provides researchers with a useful reagent to study nuclear function, gene regulation, and protein-protein interaction networks.

MPN domain-containing protein belongs to a family of proteins characterized by the Mpr1-Pad1 N-terminal (MPN) domain, which is present in many regulators of the ubiquitin-proteasome system. Research using MPND antibody has shown that it localizes to the nucleus and may contribute to the organization of transcriptional complexes. While its precise molecular role remains under investigation, its structural domain suggests functions in ubiquitin signaling and protein turnover.

Studies with MPND antibody have demonstrated that the protein interacts with chromatin and associates with regulators of gene expression. These interactions suggest that MPN domain-containing protein modulates transcription indirectly through protein scaffolding or chromatin remodeling. This places MPND at the intersection of nuclear structure and gene regulation.

Dysregulation of MPND expression has been observed in certain cancers. Research using MPND antibody has linked altered expression to tumor progression, possibly through changes in nuclear architecture and transcriptional regulation. These findings indicate that MPN domain-containing protein may function as a modulator of cellular growth and survival pathways.

MPND antibody is commonly applied in western blotting, immunohistochemistry, and immunofluorescence. Western blotting detects expression in cultured cells and tissues, immunohistochemistry identifies nuclear expression patterns, and immunofluorescence highlights nuclear localization. These approaches make MPND antibody valuable for exploratory studies into nuclear biology.

UniProt: Q8N594