KLHL12 Antikörper (AA 23-327)

Produktnummer ABIN7872525

Der Kaninchen Polyklonal anti-KLHL12 Antikörper wird verwendet zum Nachweis von KLHL12 in Proben von Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für KLHL12 Antikörper (AA 23-327) (ABIN7872525)

Target: KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLHL12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KLHL12 Antikörper

Bindungsspezifität: AA 23-327

Verwendungszweck: Zebrafish Klhl12 Antibody / Kelch-like protein 12

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Klhl12 recombinant protein (amino acids R23-V327) was used as the immunogen for the Zebrafish Klhl12 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish Klhl12 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish Klhl12 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu KLHL12

Target: KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

Andere Bezeichnung: Klhl12

Hintergrund: Kelch-like protein 12 is a protein that in humans is encoded by the KLHL12 gene. This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants.

UniProt: Q5U374