GATA2 Antikörper (AA 23-288)

Produktnummer ABIN7872522

Der Kaninchen Polyklonal anti-GATA2 Antikörper wird verwendet zum Nachweis von GATA2 in Proben von Human. Er wurde validiert für WB, ELISA, IF und FACS.

Kurzübersicht für GATA2 Antikörper (AA 23-288) (ABIN7872522)

Target: GATA2 (GATA Binding Protein 2 (GATA2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GATA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-GATA2 Antikörper

Bindungsspezifität: AA 23-288

Verwendungszweck: GATA2 Antibody

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids D23-S288) was used as the immunogen for the GATA2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the GATA2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the GATA2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu GATA2

Target: GATA2 (GATA Binding Protein 2 (GATA2))

Andere Bezeichnung: GATA2

Hintergrund: GATA2 (GATA binding protein 2) is a human gene which makes a protein called GATA binding protein 2 - a transcription factor. The GATA family of transcription factors, which contain zinc fingers in their DNA binding domain, have emerged as candidate regulators of gene expression in hematopoietic cells. Ciciotte et al.(1997)mapped the mouse Gata2 gene to chromosome 6 by study of DNA from an interspecific backcross panel. They pointed out that the human gene had been mapped to chromosome 3 by Dorfman et al.(1992) using DNA from a panel of 12 rodent/human hybrids containing various human chromosomes and applying Southern blot analysis. By exon trapping using a PAC contig spanning a breakpoint region associated with myeloid leukemia, Wieser et al.(2000) mapped the GATA2 gene to chromosome 3q21. GATA2 is transcribed from telomere to centromere. GATA2 is expressed in hematopoietic progenitors, including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells.

UniProt: P23769

Pathways: Stem Cell Maintenance