Rekombinanter Synaptophysin Antikörper (AA 224-313)

Produktnummer ABIN7872392

Dieser Maus Monoklonal Antikörper detektiert spezifisch Synaptophysin in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter Synaptophysin Antikörper (AA 224-313) (ABIN7872392)

Target: Synaptophysin (SYP)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Synaptophysin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RSYP-8807

Produktdetails anti-Synaptophysin Antikörper

Bindungsspezifität: AA 224-313

Verwendungszweck: SYP Antibody / Synaptophysin

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 224-313) from the human protein was used as the immunogen for the SYP antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SYP antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the SYP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Synaptophysin

Target: Synaptophysin (SYP)

Andere Bezeichnung: SYP

Hintergrund: This recombinant mouse monoclonal antibody recognizes a protein of 38 kDa that is identified as synaptophysin. It is an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel.This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.

UniProt: P08247

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity