JAG2 Antikörper (AA 22-1153)

Produktnummer ABIN7872266

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch JAG2 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für JAG2 Antikörper (AA 22-1153) (ABIN7872266)

Target: JAG2 (Jagged 2 (JAG2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JAG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-JAG2 Antikörper

Bindungsspezifität: AA 22-1153

Verwendungszweck: JAG2 Antibody / Jagged 2

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived human recombinant protein (amino acids Q22-N1153) was used as the immunogen for the JAG2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the JAG2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the JAG2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu JAG2

Target: JAG2 (Jagged 2 (JAG2))

Andere Bezeichnung: JAG2

Hintergrund: Protein jagged-2, also known as SER2, is a protein that in humans is encoded by the JAG2 gene. It is mapped to 14q32.33. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Notch ligands Delta1 and JAG2 are subject to presenilin-dependent, intramembranous gamma-secretase processing, resulting in the production of soluble intracellular derivatives. JAG2 can promote the growth and dissemination of uveal melanoma cells.

UniProt: Q9Y219

Pathways: Notch Signalweg, Sensory Perception of Sound