MUC2 Antikörper (AA 21-255)

Produktnummer ABIN7872156

Der Kaninchen Polyklonal anti-MUC2 Antikörper wird verwendet zum Nachweis von MUC2 in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA und IHC (p).

Kurzübersicht für MUC2 Antikörper (AA 21-255) (ABIN7872156)

Target: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUC2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MUC2 Antikörper

Bindungsspezifität: AA 21-255

Verwendungszweck: Mucin 2 Antibody / MUC2

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids S21-C255) was used as the immunogen for the Mucin 2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Mucin 2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Mucin 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu MUC2

Target: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Andere Bezeichnung: Mucin 2

Hintergrund: Mucin 2, also known as MUC2, is a protein that in humans is encoded by the MUC2 gene. This gene encodes a member of the mucin protein family. It is mapped to 11p15.5. Mucin 2 is particularly prominent in the gut where it is secreted from goblet cells in the epithelial lining into the lumen of the large intestine. There, mucin 2, along with small amounts of related-mucin proteins, polymerizes into a gel of which 80 % by weight is oligosaccharide side-chains that are added as post-translational modifications to the mucin proteins. This gel provides an insoluble mucous barrier that serves to protect the intestinal epithelium. The primary function of the MUC2 gene product is to provide a protective barrier between the epithelial surfaces and the gut lumen. There is decreased expression of MUC2 in colonic cancer and defective polymerization of secreted mucin in ulcerative colitis.

UniProt: Q02817