NHP2 Antikörper (AA 21-136)

Produktnummer ABIN7872130

Der Kaninchen Polyklonal anti-NHP2 Antikörper (ABIN7872130) detektiert spezifisch NHP2 in ELISA, WB, IF, IP und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für NHP2 Antikörper (AA 21-136) (ABIN7872130)

Target: NHP2 (NHP2 Ribonucleoprotein (NHP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NHP2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Produktdetails anti-NHP2 Antikörper

Bindungsspezifität: AA 21-136

Verwendungszweck: NHP2 Antibody / H/ACA ribonucleoprotein complex subunit 2

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids E21-Q136) was used as the immunogen for the NHP2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the NHP2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the NHP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu NHP2

Target: NHP2 (NHP2 Ribonucleoprotein (NHP2))

Andere Bezeichnung: NHP2

Hintergrund: This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants.

UniProt: Q9NX24

Pathways: Telomere Maintenance