Apolipoprotein D Antikörper (AA 21-119)

Produktnummer ABIN7872125

Dieser Maus Monoklonal Antikörper detektiert spezifisch Apolipoprotein D in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Apolipoprotein D Antikörper (AA 21-119) (ABIN7872125)

Target: Apolipoprotein D (APOD)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Apolipoprotein D Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: APOD-3415

Produktdetails anti-Apolipoprotein D Antikörper

Bindungsspezifität: AA 21-119

Verwendungszweck: APOD Antibody / Apolipoprotein D

Aufreinigung: Protein A/G affinity

Immunogen: A portin of amino acids 21-119 from the human protein was used as the immunogen for the APOD antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the APOD antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the APOD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Apolipoprotein D

Target: Apolipoprotein D (APOD)

Andere Bezeichnung: APOD

Hintergrund: Lipids, such as phospholipids, triacylglycerols and cholesterol, are weakly soluble in aqueous solution and therefore are transported by circulation as components of lipoproteins. Lipoproteins are globular particles that consist of a non-polar core of triacylglycerols and cholesteryl esters surrounded by phospholipid, cholesterol and an amphiphilic coating of protein, known as apolipoproteins (apo). These complexes allow the dissolution and shuttling of their non-polar lipid components. At least nine different apolipoproteins are distributed in significant amounts in different human lipoproteins. Apolipoprotein D (apoD) is a member of the lipocalin superfamily of transporter proteins that bind small hydrophobic molecules, including arachidonic acid (AA). The ability of apoD to bind AA implicates it in pathways associated with membrane phospholipid signal transduction and metabolism. apoD expression has been shown to correlate both with cell cycle arrest and with prognosis in several types of malignancy, including central nervous system astrocytomas and medulloblastomas.

UniProt: P05090

Pathways: Platelet-derived growth Factor Receptor Signaling