CFHR5 Antikörper (AA 203-231)

Produktnummer ABIN7872079

Der Kaninchen Polyklonal anti-CFHR5 Antikörper (ABIN7872079) detektiert spezifisch CFHR5 in WB, FACS und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CFHR5 Antikörper (AA 203-231) (ABIN7872079)

Target: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CFHR5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CFHR5 Antikörper

Bindungsspezifität: AA 203-231

Verwendungszweck: FHR-5 Antibody / Complement factor H-related protein 5 / CFHR5

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 203-231 from the human protein was used as the immunogen for the FHR-5 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the FHR-5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the FHR-5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu CFHR5

Target: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Andere Bezeichnung: FHR-5

Hintergrund: CFHR5 / FHR-5 is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq].

UniProt: Q9BXR6