METAP2 Antikörper (AA 201-474)

Produktnummer ABIN7872075

Der Kaninchen Polyklonal anti-METAP2 Antikörper wird verwendet zum Nachweis von METAP2 in Proben von Human, Maus, Ratte und Affe. Er wurde validiert für WB, ELISA und IHC (p).

Kurzübersicht für METAP2 Antikörper (AA 201-474) (ABIN7872075)

Target: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser METAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-METAP2 Antikörper

Bindungsspezifität: AA 201-474

Verwendungszweck: METAP2 Antibody / Methionine aminopeptidase 2

Aufreinigung: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (E201-R474) was used as the immunogen for the METAP2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the METAP2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the METAP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu METAP2

Target: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Andere Bezeichnung: METAP2

Hintergrund: Methionine aminopeptidase 2 is an enzyme that in humans is encoded by the METAP2 gene. The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene.

UniProt: P50579

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling