Rekombinanter Splicing Factor 1 Antikörper (AA 200-400)
Kurzübersicht für Rekombinanter Splicing Factor 1 Antikörper (AA 200-400) (ABIN7872052)
Target
Alle Splicing Factor 1 (SF1) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- AA 200-400
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Verwendungszweck
- SF-1 Antibody / Steroidogenic Factor 1 / NR5A1 (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- A recombinant partial protein sequence (within amino acids 200-400) from the human protein was used as the immunogen for the SF-1 antibody.
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Isotyp
- IgG, kappa
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Applikationshinweise
- Optimal dilution of the SF-1 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the SF-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Splicing Factor 1 (SF1)
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Andere Bezeichnung
- SF-1
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Hintergrund
- Steroidogenic Factor 1 (SF-1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development.SF-1 is highly valuable marker to determine the adrenocortical origin of an adrenal mass.
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UniProt
- Q13285
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Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Maintenance of Protein Location
Target
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