PAX2A Antikörper (AA 200-400)

Produktnummer ABIN7872035

Dieser Maus Monoklonal Antikörper detektiert spezifisch PAX2A in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PAX2A Antikörper (AA 200-400) (ABIN7872035)

Target: PAX2A (Paired Box Gene 2a (PAX2A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PAX2A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: PAX2-2994

Produktdetails anti-PAX2A Antikörper

Bindungsspezifität: AA 200-400

Verwendungszweck: PAX2 Antibody

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein (within amino acids 200-400) from the human protein was used as the immunogen for the PAX2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PAX2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the PAX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu PAX2A

Target: PAX2A (Paired Box Gene 2a (PAX2A))

Andere Bezeichnung: PAX2

Hintergrund: Recognizes a protein of 42 kDa, which is identified as PAX2. It is a member of the paired box family of transcription factors, which is required for development and proliferation of the kidney, brain, and mullerian organs. PAX2 genes contain a highly conserved DNA sequence within the paired box region, which encodes a DNA-binding domain, enabling PAX proteins to bind the promoters of specific genes to transcriptionally regulate their expression. PAX2 is specifically expressed in the developing central nervous system, eye, ear, and urogenital tract, and is essential for the development of these organs. In normal adult tissues PAX2 was mainly detected in the urogenital system, including kidney, ureteric epithelium, fallopian tube epithelium, ovary and uterus. In tumors, PAX2 has been detected in renal cell carcinomas, Wilms' tumors, nephrogenic adenomas and papillary serous carcinoma of the ovary. PAX2 has been used as a marker for the identification of renal cell carcinoma and ovarian carcinoma by immunohistochemistry.

UniProt: Q02962

Pathways: Carbohydrate Homeostasis, Stem Cell Maintenance, Tube Formation