Rekombinanter SFTPD Antikörper (AA 200-375)

Produktnummer ABIN7871989

Der Maus Monoklonal anti-SFTPD Antikörper (Klon rSFTPD-8064) (ABIN7871989) detektiert spezifisch SFTPD in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter SFTPD Antikörper (AA 200-375) (ABIN7871989)

Target: SFTPD (Surfactant Protein D (SFTPD))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SFTPD Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RSFTPD-8064

Produktdetails anti-SFTPD Antikörper

Bindungsspezifität: AA 200-375

Verwendungszweck: Surfactant protein D Antibody

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein (within amino acids 200-375) from the human protein was used as the immunogen for the Surfactant protein D antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Surfactant protein D antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Surfactant protein D antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu SFTPD

Target: SFTPD (Surfactant Protein D (SFTPD))

Andere Bezeichnung: Surfactant protein D

Hintergrund: Pulmonary surfactant is primarily responsible for lowering the surface tension at the air-liquid interface in the alveoli, a process that is essential for normal respiration. Pulmonary surfactant is a mixture of phospholipids and proteins, including four distinct surfactant-associated proteins (SPs), SP-A, SP-B, SP-C, SP-D. SP-B and SP-C are predominantly hydrophobic proteins that associate with lipids to promote the absorption of surfactant phospholipids and to reduce the surface tension in the alveoli. SP-A and SP-D are large multimeric proteins belonging to the family of calcium-dependent lectins, designated Collectins, which contribute to the innate immune system. Both SP-A and SP-D have been shown to protect against microbial challenge through binding to the lipid components of the bacterial cell wall and facilitating the rapid removal of microbials.

UniProt: P35247