CXCR4 Antikörper (AA 20-352)
Kurzübersicht für CXCR4 Antikörper (AA 20-352) (ABIN7871865)
Target
Alle CXCR4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 20-352
-
Verwendungszweck
- CXCR4 Antibody
-
Aufreinigung
- Affinity purified
-
Immunogen
- An E. coli-derived human protein (amino acids D20-S352) was used as the immunogen for the CXCR4 antibody.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Optimal dilution of the CXCR4 antibody should be determined by the researcher.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- After reconstitution, the CXCR4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
-
Andere Bezeichnung
- CXCR4
-
Hintergrund
- CXCR4 (Chemokine, CXC Motif, Receptor 4), also known as FUSIN or NPY3R, is a protein that in humans is encoded by the CXCR4 gene. It is the receptor for the CXC chemokine SDF1 that has essential functions on embryo organogenesis, immunological functions and T lymphocyte trafficking. CXCR4 is the only SDF1 receptor identified so far. This suggests that CXCR4 expression is critical for the biological effects of SDF1. CXCR4 is also a seven-transmembrane-spanning, G-protein-coupled receptor for the CXC chemokine PBSF/SDF-1. It functions as a co-receptor for T-cell-line tropic human immunodeficiency virus HIV-1. It was concluded that PBSF/SDF-1 and CXCR4 define a new signaling system for organ vascularization.
-
UniProt
- P61073
-
Pathways
- Regulation of Cell Size, CXCR4-mediated Signaling Events
Target
-