PON1 Antikörper (AA 20-252)

Produktnummer ABIN7871850

Der Kaninchen Polyklonal anti-PON1 Antikörper wird verwendet zum Nachweis von PON1 in Proben von Human, Maus, Ratte und Affe. Er wurde validiert für WB, ELISA und IHC (p).

Kurzübersicht für PON1 Antikörper (AA 20-252) (ABIN7871850)

Target: PON1 (Paraoxonase 1 (PON1))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PON1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PON1 Antikörper

Bindungsspezifität: AA 20-252

Verwendungszweck: Paraoxonase 1 Antibody / PON1

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids H20-A252) was used as the immunogen for the Paraoxonase 1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Paraoxonase 1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Paraoxonase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu PON1

Target: PON1 (Paraoxonase 1 (PON1))

Andere Bezeichnung: Paraoxonase 1

Hintergrund: Serum paraoxonase/arylesterase 1 (PON1), also known as aromatic esterase 1, is an enzyme that in humans is encoded by the PON1 gene. It is mapped to 7q21.3. This gene has esterase and more specifically paraoxonase activity. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL). The PON1 gene is activated by PPAR-?, which increases synthesis and release of paraoxonase 1 enzyme from the liver, reducing atherosclerosis.

UniProt: P27169