Der Kaninchen Polyklonal anti-DOCK4 Antikörper wird verwendet zum Nachweis von DOCK4 in Proben von Human und Ratte. Er wurde validiert für WB, ELISA, IHC (p) und FACS.
DOCK4
Reaktivität: Human
IF (p), IF (cc)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 555
Applikationshinweise
Optimal dilution of the DOCK4 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
After reconstitution, the DOCK4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
DOCK4
(Dedicator of Cytokinesis 4 (DOCK4))
Andere Bezeichnung
DOCK4
Hintergrund
This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized.