MFAP3 Antikörper (AA 19-349)

Produktnummer ABIN7871588

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MFAP3 in ELISA, WB, FACS und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für MFAP3 Antikörper (AA 19-349) (ABIN7871588)

Target: MFAP3 (Microfibrillar Associated Protein 3 (MFAP3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MFAP3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MFAP3 Antikörper

Bindungsspezifität: AA 19-349

Verwendungszweck: MFAP3 Antibody / Microfibril-associated glycoprotein 3

Aufreinigung: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (A19-N349) was used as the immunogen for the MFAP3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the MFAP3 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the MFAP3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu MFAP3

Target: MFAP3 (Microfibrillar Associated Protein 3 (MFAP3))

Andere Bezeichnung: MFAP3

Hintergrund: Microfibril-associated glycoprotein 3 (MFAP3), is a member of the MFAP family which play a role in microfibril assembly, elastinogenesis, and tissue homeostasis. The family members were identified as potential components of fibrillin-containing microfibrils, but they do not share structural similarities. MFAP3 is found in ocular zonules. Human MFAP3 is a serine-rich acidic protein located in zonular fibers and consists of an extracellular domain (ECD) containing one Ig-like C2-type domain, a single transmembrane domain, and a cytoplasmic domain. Within the ECD, mature human MFAP3 shares 74 % amino acid sequence identity with mouse and rat MFAP3. Among MFAP3-related pathways are degradation of the extracellular matrix and elastic fiber formation. MFAP is a candidate gene for heritable diseases affecting microfibrils.

UniProt: P55082