PHTF1 Antikörper (AA 188-430)

Produktnummer ABIN7871517

Der Kaninchen Polyklonal anti-PHTF1 Antikörper wird verwendet zum Nachweis von PHTF1 in Proben von Human. Er wurde validiert für WB, ELISA und FACS.

Kurzübersicht für PHTF1 Antikörper (AA 188-430) (ABIN7871517)

Target: PHTF1 (Putative Homeodomain Transcription Factor 1 (PHTF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHTF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-PHTF1 Antikörper

Bindungsspezifität: AA 188-430

Verwendungszweck: PHTF1 Antibody / Putative homeodomain transcription factor 1

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids I188-Q430) was used as the immunogen for the PHTF1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PHTF1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the PHTF1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu PHTF1

Target: PHTF1 (Putative Homeodomain Transcription Factor 1 (PHTF1))

Andere Bezeichnung: PHTF1

Hintergrund: PHTF1 (putative homeodomain transcription factor 1), also known as PHTF, is a potential transcription regulator. It is a ubiquitously expressed integral, multipass membrane protein with predominant expression in testis. PHTF1 is associated with the ER (endoplasmic reticulum) and contains one bHLH (basic helix-loop-helix) domain. It is present in the cell during meiosis and spermiogenesis but, by the end of spermiogenesis, is released from the mature cell within the residual bodies. This implies that PHTF1 may play a role in the spermatozoa maturation process. In addition, PHTF1 is believed to interact with FEM1B and may be responsible for recruiting FEM1B to the surface of the ER membrane. This suggests that PHTF1 acts as a sequestering or anchoring protein for FEM1B. Two PHTF1 isoforms exist due to alternate splicing events. Isoform 2 is the shorter form and lacks the amino acid residues 648 to 762.

UniProt: Q9UMS5