Prosaposin Antikörper (AA 182-479)

Produktnummer ABIN7871467

Der Kaninchen Polyklonal anti-Prosaposin Antikörper (ABIN7871467) detektiert spezifisch Prosaposin in WB, ELISA, IF, IHC (p) und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Prosaposin Antikörper (AA 182-479) (ABIN7871467)

Target: Prosaposin (PSAP)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prosaposin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-Prosaposin Antikörper

Bindungsspezifität: AA 182-479

Verwendungszweck: Prosaposin Antibody / PSAP

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids Q182-I479) was used as the immunogen for the Prosaposin antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Prosaposin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Prosaposin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Prosaposin

Target: Prosaposin (PSAP)

Andere Bezeichnung: Prosaposin

Hintergrund: This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

UniProt: P07602

Pathways: Positive Regulation of Endopeptidase Activity