H2AFY Antikörper (AA 180-301)

Produktnummer ABIN7871442

Der Kaninchen Polyklonal anti-H2AFY Antikörper wird verwendet zum Nachweis von H2AFY in Proben von Human, Ratte und Maus. Er wurde validiert für WB, IF, ELISA und IHC (p).

Kurzübersicht für H2AFY Antikörper (AA 180-301) (ABIN7871442)

Target: H2AFY (H2A Histone Family, Member Y (H2AFY))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser H2AFY Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-H2AFY Antikörper

Bindungsspezifität: AA 180-301

Verwendungszweck: MACROH2A1 Antibody / Core histone macro-H2A.1 / H2AFY

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived human recombinant protein (amino acids A180-K301) was used as the immunogen for the MACROH2A1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the MACROH2A1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the MACROH2A1 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu H2AFY

Target: H2AFY (H2A Histone Family, Member Y (H2AFY))

Andere Bezeichnung: MACROH2A1

Hintergrund: Core histone macro-H2A.1 is a protein that in humans is encoded by the MACROH2A1 gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: O75367