Der Kaninchen Polyklonal anti-FOLR2 Antikörper wird verwendet zum Nachweis von FOLR2 in Proben von Human und Maus. Er wurde validiert für WB, FACS und IHC (p).
The stated application concentrations are suggested starting points. Titration of the FOLR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the FOLR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
FOLR2
(Folate Receptor 2 (Fetal) (FOLR2))
Andere Bezeichnung
FOLR2
Hintergrund
FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.