SELPLG Antikörper (AA 18-420)

Produktnummer ABIN7871418

Der Kaninchen Polyklonal anti-SELPLG Antikörper wird verwendet zum Nachweis von SELPLG in Proben von Maus und Ratte. Er wurde validiert für FACS, WB, ELISA und IHC (p).

Kurzübersicht für SELPLG Antikörper (AA 18-420) (ABIN7871418)

Target: SELPLG (Selectin P Ligand (SELPLG))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SELPLG Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SELPLG Antikörper

Bindungsspezifität: AA 18-420

Verwendungszweck: Psgl-1 Antibody / Selplg

Aufreinigung: Affinity purified

Immunogen: Recombinant rat protein (amino acids L18-P420) was used as the immunogen for the Psgl-1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Psgl-1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Psgl-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu SELPLG

Target: SELPLG (Selectin P Ligand (SELPLG))

Andere Bezeichnung: Psgl-1

Hintergrund: Selectin P ligand, also known as SELPLG or CD162 (cluster of differentiation 162), is a human gene. It is mapped to 12q16. This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.

UniProt: Q8K5B0