D Amino Acid Oxidase Antikörper (AA 18-338)

Produktnummer ABIN7871408

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch D Amino Acid Oxidase in WB, ELISA und FACS. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für D Amino Acid Oxidase Antikörper (AA 18-338) (ABIN7871408)

Target: D Amino Acid Oxidase (DAO) (D-Amino-Acid Oxidase (DAO))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser D Amino Acid Oxidase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-D Amino Acid Oxidase Antikörper

Bindungsspezifität: AA 18-338

Verwendungszweck: D-amino-acid oxidase Antibody / DAO

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids C18-K338) was used as the immunogen for the D-amino-acid oxidase antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the D-amino-acid oxidase antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the D-amino-acid oxidase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu D Amino Acid Oxidase

Target: D Amino Acid Oxidase (DAO) (D-Amino-Acid Oxidase (DAO))

Andere Bezeichnung: D-amino-acid oxidase

Hintergrund: D-amino acid oxidase (DAAO, also OXDA, DAMOX) is an enzyme with the function on a molecular level to oxidize D-amino acids to the corresponding alpha-keto acids, producing ammonia and hydrogen peroxide. This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known, it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.

UniProt: P14920