Sorbs2 Antikörper (AA 175-204)

Produktnummer ABIN7871302

Der Kaninchen Polyklonal anti-Sorbs2 Antikörper (ABIN7871302) detektiert spezifisch Sorbs2 in WB, IHC (p), FACS und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Sorbs2 Antikörper (AA 175-204) (ABIN7871302)

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sorbs2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails anti-Sorbs2 Antikörper

Bindungsspezifität: AA 175-204

Verwendungszweck: SORBS2 Antibody / ARGBP2

Aufreinigung: Purified

Immunogen: A portion of amino acids 175-204 from the human protein was used as the immunogen for the SORBS2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the SORBS2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the SORBS2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Sorbs2

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Andere Bezeichnung: SORBS2

Hintergrund: Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. ARGBP2 is the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton.

UniProt: O94875