ZNF488 Antikörper (AA 170-307)

Produktnummer ABIN7871250

Der Maus Monoklonal anti-ZNF488 Antikörper wird verwendet zum Nachweis von ZNF488 in Proben von Human. Er wurde validiert für FACS und IHC (p).

Kurzübersicht für ZNF488 Antikörper (AA 170-307) (ABIN7871250)

Target: ZNF488 (Zinc Finger Protein 488 (ZNF488))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ZNF488 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: PCRP-ZNF488-2D8

Produktdetails anti-ZNF488 Antikörper

Bindungsspezifität: AA 170-307

Verwendungszweck: ZNF488 Antibody

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein (within amino acids 170-307) from the human protein was used as the immunogen for the ZNF488 antibody.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ZNF488 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the ZNF488 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu ZNF488

Target: ZNF488 (Zinc Finger Protein 488 (ZNF488))

Andere Bezeichnung: ZNF488

Hintergrund: Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF488 is a 340 amino acid transcriptional regulator belonging to the Kruppel C2H2-type zinc finger protein family. ZNF488 localizes to the nucleus and contains two C2H2-type zinc fingers. ZNF488 is encoded by a gene located on chromosome 10, which contains a plethora of interesting genes and represents between 4 and 4.5 percent of the total DNA in cells. Jackson-Weiss, Cowden and Usher syndromes are a few diseases related to genes on chromosome 10.

UniProt: Q96MN9