MOV10 Antikörper (AA 167-772)

Produktnummer ABIN7871196

Der Kaninchen Polyklonal anti-MOV10 Antikörper wird verwendet zum Nachweis von MOV10 in Proben von Human. Er wurde validiert für WB, ELISA, IF, IHC (p) und FACS.

Kurzübersicht für MOV10 Antikörper (AA 167-772) (ABIN7871196)

Target: MOV10 (Moloney Leukemia Virus 10 (MOV10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MOV10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-MOV10 Antikörper

Bindungsspezifität: AA 167-772

Verwendungszweck: MOV10 Antibody

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids H167-Q772) was used as the immunogen for the MOV10 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the MOV10 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the MOV10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu MOV10

Target: MOV10 (Moloney Leukemia Virus 10 (MOV10))

Andere Bezeichnung: MOV10

Hintergrund: Putative helicase MOV-10 is an enzyme that in humans is encoded by the MOV10 gene. MOV10, also named as KIAA1631, belongs to the DNA2/NAM7 helicase family and SDE3 subfamily. It is required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Human MOV10 may regulate a wide range of RNA viruses and could also control the retro-transposition of endogenous retroelements in mammals. MOV10 has a broad antiretroviral activity that can target a wide range of retroviruses, and it could be actively involved in host defense against retroviral infection. MOV10 can potently inhibit HIV-1 replication at multiple stages. It is involved in the progression of telomerase-catalyzing reaction via the interaction of telomerase protein and telomere DNA.

UniProt: Q9HCE1

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, SARS-CoV-2 Protein Interaktom