AFG3L2 Antikörper (AA 161-245)

Produktnummer ABIN7871108

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch AFG3L2 in WB. Es zeigt Reaktivität gegenüber Proben von Zebrafisch (Danio rerio).

Kurzübersicht für AFG3L2 Antikörper (AA 161-245) (ABIN7871108)

Target: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AFG3L2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AFG3L2 Antikörper

Bindungsspezifität: AA 161-245

Verwendungszweck: Zebrafish Afg3l2 Antibody / AFG3 like protein 2

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Afg3l2 recombinant protein (amino acids G161-D245) was used as the immunogen for the Zebrafish Afg3l2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish Afg3l2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish Afg3l2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu AFG3L2

Target: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Andere Bezeichnung: Afg3l2

Hintergrund: AFG3L2 is the catalytic subunit of the m-AAA protease, an ATP-dependent proteolytic complex of the mitochondrial inner membrane that degrades misfolded proteins and regulates ribosome assembly. In humans, it is encoded by the AFG3L2 gene. This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. And this gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders as well as spastic ataxia-neuropathy syndrome.

UniProt: A9JRG9

Pathways: Skeletal Muscle Fiber Development