Cadherin 13 Antikörper (AA 149-692)

Produktnummer ABIN7870778

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Cadherin 13 in WB, ELISA, IF, FACS und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für Cadherin 13 Antikörper (AA 149-692) (ABIN7870778)

Target: Cadherin 13 (CDH13)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Cadherin 13 Antikörper

Bindungsspezifität: AA 149-692

Verwendungszweck: Cadherin 13 Antibody / CDH13 / H Cadherin

Aufreinigung: Affinity purified

Immunogen: A human recombinant partial protein (amino acids E149-A692) was used as the immunogen for the Cadherin 13 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Cadherin 13 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Cadherin 13 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Cadherin 13

Target: Cadherin 13 (CDH13)

Andere Bezeichnung: Cadherin 13

Hintergrund: H-cadherin (CDH13) is a unique member of cadherin superfamily because it lacks the transmembrane and cytoplasmic domains and is anchored to the cells membrane through the GPI anchor. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: P55290

Pathways: EGFR Signaling Pathway, Cell-Cell Junction Organization