LCK Antikörper (pTyr505) (Cy7)

Produktnummer ABIN743594

Der Kaninchen Polyklonal Anti-LCK-Antikörper wurde für IF (cc) und IF (p) validiert. Er ist geeignet, LCK in Proben von Human zu detektieren.

Kurzübersicht für LCK Antikörper (pTyr505) (Cy7) (ABIN743594)

Target: LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LCK Antikörper ist konjugiert mit Cy7

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-LCK Antikörper (Cy7)

Bindungsspezifität: pTyr505

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Lck around the phosphorylation site of Tyr505

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu LCK

Target: LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))

Andere Bezeichnung: LCK

Hintergrund:

Synonyms: LCK phospho Y505, LCK phospho Tyr505, p-LCK Tyr505, p56-LCK, Lymphocyte cell-specic protein-tyrosine kinase, LSK, T cell-specic protein-tyrosine kinase, Lck p56, LSK, Lymphocyte Specic Protein Tyrosine Kinase, Membrane associated protein tyrosine kinase, Oncogene lck, P56 LCK, p56LSTRA protein tyrosine kinase, p56lck, pp58 lck, pp58lck, Proto oncogene tyrosine protein kinase LCK, Protooncogene tyrosine protein kinase LCK, T cell specic protein tyrosine kinase, T lymphocyte specic protein tyrosine kinase p56lck, YT 16, YT16, LCK_HUMAN.

Background: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008].

Gen-ID: 3932

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling