SOX3 Antikörper (AA 141-285)

Produktnummer ABIN7870673

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SOX3 in WB. Es zeigt Reaktivität gegenüber Proben von Zebrafisch (Danio rerio).

Kurzübersicht für SOX3 Antikörper (AA 141-285) (ABIN7870673)

Target: SOX3 (SRY (Sex Determining Region Y)-Box 3 (SOX3))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SOX3 Antikörper

Bindungsspezifität: AA 141-285

Verwendungszweck: Zebrafish Sox3 Antibody / SRY-box 3

Aufreinigung: Antigen affinity chromatography

Immunogen: E. coli-derived zebrafish Sox3 recombinant protein (amino acids Q141-Q285) was used as the immunogen for the Zebrafish Sox3 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish Sox3 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish Sox3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu SOX3

Target: SOX3 (SRY (Sex Determining Region Y)-Box 3 (SOX3))

Andere Bezeichnung: Sox3

Hintergrund: SRY-box transcription factor 3 (Sox3) is a member of the SoxB1 subfamily of transcription factors, which are key regulators of early embryonic development and neural differentiation. In zebrafish (Danio rerio), Sox3 plays a critical role in the formation of the nervous system, maintenance of neural progenitor identity, and early ectodermal patterning.

Sox3 is maternally deposited and is expressed in the neuroectoderm during early development. It acts as a transcriptional activator that promotes neural fate by regulating genes involved in progenitor cell maintenance and inhibiting premature neuronal differentiation. Sox3 also contributes to the development of the pituitary gland, sensory placodes, and hypothalamic structures.

Due to its conservation across vertebrates, zebrafish Sox3 serves as a powerful model for studying neurogenesis, pluripotency, and transcriptional regulation during early embryonic development. It is also used to investigate mechanisms of cell fate decisions, stem cell biology, and congenital neurological disorders.

UniProt: Q6EJB7