PRDM8 Antikörper (AA 14-405)

Produktnummer ABIN7870635

Der Kaninchen Polyklonal anti-PRDM8 Antikörper wird verwendet zum Nachweis von PRDM8 in Proben von Human. Er wurde validiert für WB, ELISA, IF und FACS.

Kurzübersicht für PRDM8 Antikörper (AA 14-405) (ABIN7870635)

Target: PRDM8 (PR Domain Containing 8 (PRDM8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRDM8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-PRDM8 Antikörper

Bindungsspezifität: AA 14-405

Verwendungszweck: PRDM8 Antibody / PR domain zinc finger protein 8

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids D14-D405) was used as the immunogen for the PRDM8 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PRDM8 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the PRDM8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu PRDM8

Target: PRDM8 (PR Domain Containing 8 (PRDM8))

Andere Bezeichnung: PRDM8

Hintergrund: This gene encodes a protein that belongs to a conserved family of histone methyltransferases that predominantly act as negative regulators of transcription. The encoded protein contains an N-terminal Su(var)3-9, Enhancer-of-zeste, and Trithorax (SET) domain and a double zinc-finger domain. Knockout of this gene in mouse results in mistargeting by neurons of the dorsal telencephalon, abnormal itch-like behavior, and impaired differentiation of rod bipolar cells. In humans, the protein has been shown to interact with the phosphatase laforin and the ubiquitin ligase malin, which regulate glycogen construction in the cytoplasm. Alternative splicing results in multiple transcript variants.

UniProt: Q9NQV8