ADRM1 Antikörper (AA 14-385)

Produktnummer ABIN7870629

Der Kaninchen Polyklonal anti-ADRM1 Antikörper wird verwendet zum Nachweis von ADRM1 in Proben von Zebrafisch (Danio rerio). Er wurde validiert für WB und IHC (p).

Kurzübersicht für ADRM1 Antikörper (AA 14-385) (ABIN7870629)

Target: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ADRM1 Antikörper

Bindungsspezifität: AA 14-385

Verwendungszweck: Zebrafish Adrm1 Antibody / Adrm1b

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Adrm1 recombinant protein (amino acids S14-M385) was used as the immunogen for the Zebrafish Adrm1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish Adrm1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish Adrm1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu ADRM1

Target: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Andere Bezeichnung: Adrm1

Hintergrund: Proteasomal ubiquitin receptor ADRM1 is a protein that in humans is encoded by the ADRM1 gene. This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants.

UniProt: Q6NZ09

Pathways: Positive Regulation of Endopeptidase Activity